Sara Webb received her early training at the Academy of Nevada Dance Theatre and at the Harid Conservatory in Boca Raton, Florida, from which she graduated in 1996. Ms. Webb was invited to join Houston Ballet in 1997.  She was promoted to principal in 2003.  She has performed the lead roles in a number of Ben Stevenson's classical productions, including Aurora and Blue Bird in The Sleeping Beauty, Juliet in Romeo and Juliet, Odette/Odile in Swan Lake, Kitri in Don Quixote, Swanilda in Coppélia, Alice and Tiger Lily in Alice in Wonderland, Cinderella in Cinderella, Svetlana in Dracula, the pas de deux from Esmeralda, and both Sugar Plum Fairy and Snow Queen in The Nutcracker. Equally familiar with the work of other classical choreographers, she has also been featured in the lead roles in Sir Frederick Ashton's La Fille Mal Gardée; Johnny Eliasen's staging of La Sylphide; Stanton Welch's Swan Lake, Madame Butterfly and Marie; John Cranko's The Taming of the Shrew (Bianca); Sir Kenneth MacMillan's Manon; Ai-Gul Gaisina's and Maina Gielgud's staging of Giselle; and James Kudelka's The Firebird. Trey McIntyre created and set on Ms. Webb the role of Wendy in his Peter Pan (2002) and the role of Thumbelina in The Shadow (2003). The role of Nikiya was created on Ms. Webb in Stanton Welch's 2010 staging of La Bayadère.

Ms. Webb was honored to perform Tchaikovsky Pas de Deux at the 2008 Fall For Dance Festival at City Center in New York as well as at Houston Ballet's Jubilee of Dance the same year. She was a finalist at the 2002 International Ballet Competition, performing Mr. Stevenson's Twilight, which he choreographed and set on Ms. Webb and Ian Cassidy for the competition, and they performed in its world premiere at the Bolshoi Theatre in Moscow in 2002.